Memantin HCl

Product Description

A dysfunction of glutamatergic neurotransmission, manifested as neuronal excitotoxicity, is hypothesized to be involved in the etiology of Alzheimer's disease. Targeting the glutamatergic system, specifically NMDA receptors, offers a novel approach to treatment in view of the limited efficacy of existing drugs targeting the cholinergic system.

Memantine is a low-affinity voltage-dependent uncompetitive antagonist at glutamatergic NMDA receptors. By binding to the NMDA receptor with a higher affinity than Mg2+ ions, memantine is able to inhibit the prolonged influx of Ca2+ ions which forms the basis of neuronal excitotoxicity. The low affinity and rapid off-rate kinetics of memantine at the level of the NMDA receptor-channel, however, preserves the physiological function of the receptor as it can still be activated by the relatively high concentrations of glutamate released following depolarization of the presynaptic neuron.

High-Quality Central Nervous System Agent

Memantin HCl plays a crucial role as a central nervous system agent in the pharmaceutical industry. Recognized for its superior purity and effectiveness, it contributes significantly to the development and manufacturing of medicines for cognitive disorders. We ensure strict quality control for safe and reliable use.


Exceptional Stability and Longevity

Our Memantin HCl powder boasts a shelf life of up to five years when stored under appropriate conditions. This extended stability ensures that it maintains its potency and quality, making it a practical choice for manufacturers and researchers requiring long-term storage.


Reliable Exporter and Supplier in India

As a reputable exporter, supplier, and trader based in India, we deliver Memantin HCl to both domestic and international markets. Our robust distribution network allows us to meet diverse customer needs promptly and efficiently, ensuring a consistent supply chain.