Bosentan is a mixed endothelin receptor antagonist which is used as a vasodilator. Bosentan is an inhibitor of ETAR and ETBR.
Analysis Test
Specification |
Result |
|
Description |
white crystalline powder |
Conforms |
Solubility |
Easily soluble in water, unsoluble in ethanol |
Conforms |
PH |
6.0 to 7.5 |
6.9 |
Solution clarity and color |
solution should be clear and colorless |
Conforms |
Related substances |
5CMP 0.3% |
0.01% |
Chloride |
0.05% |
Conforms |
Ammonium |
0.05% |
Conforms |
Fe |
0.01% |
Conforms |
Phosphate |
0.1% |
Conforms |
Loss on drying |
6.0% |
1.3% |
Heavy metals |
0.002% |
Conforms |
Arsenide |
0.0001% |
Conforms |
Bacterial Endotoxins |
0.3EU/mg |
Conforms |
Microbial Limit |
Conforms |
Conforms |