Amiloride HCl

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Product Details:

Storage Other
Shelf Life 5 Years
Molecular Weight 266.09 Grams (g)
Molecular Formula C6H8ClN7O.HCl
Medicine Name Amiloride HCl
CAS No 2016-88-8
Type Other
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Amiloride HCl Price And Quantity

Minimum Order Quantity 25 Kilograms

Amiloride HCl Product Specifications

Molecular Weight 266.09 Grams (g)
Molecular Formula C6H8ClN7O.HCl
Grade Medicine Grade
Usage used in the management of hypertension andcongestive heart failure.
Purity(%) 99
Storage Other
CAS No 2016-88-8
Appearance Yellow or yellow green crystalline powder
Shelf Life 5 Years
Medicine Name Amiloride HCl
Physical Form Powder
Type Other

Amiloride HCl Trade Information

FOB Port mumbai
Payment Terms Western Union Paypal Cash Advance (CA) Cash in Advance (CID)
Supply Ability 300 Kilograms Per Week
Delivery Time 15 Days
Packaging Details 25KG/Drum with double plastic bag inside; Aluminium foil bag with plastic bag inside and carton box outside for small quantity
Main Export Market(s) Central America Australia North America South America Eastern Europe Western Europe Middle East Africa Asia
Main Domestic Market All India

Product Description

potassium-sparing diuretic, used in the management of hypertension andcongestive heart failure. Amiloride was also tested as treatment ofcystic fibrosis.

Mechanism of Action:

Amiloride works by directly blocking the epithelial sodium channel(ENaC) thereby inhibiting sodium reabsorption in the late distal convoluted tubules, connecting tubules, and collecting ducts in thekidneys (this mechanism is the same for triamterene).This promotes the loss of sodium and water from the body, but without depletingpotassium. The drug is often used in conjunction with thiazide (e.g.co-amilozide) or loop diuretics (e.g. co-amilofruse). Due to its potassium-sparing capacities, hyperkalemia (high blood potassium levels) is occasionally observed in patients taking amiloride. The risk is high in concurrent use of ACE inhibitors or spironolactone.

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